Human Reproduction Update (2019 IF: 12.684) is the leading journal in its field, ranked first in the category of Obstetrics & Gynecology. The journal publishes comprehensive and systematic review articles in human reproductive physiology and medicine.
Basic, transitional and clinical topics related to reproduction are of primary interest. This includes all the relevant areas of andrology, embryology, infertility, gynaecology, pregnancy, reproductive endocrinology, reproductive epidemiology, reproductive genetics, reproductive immunology, and reproductive oncology.
Human Reproduction Update is published on behalf of the European Society of Human Reproduction and Embryology (ESHRE). The highest scientific and editorial standards are maintained.
Human Reproduction Update: advance access
- Impacts of platinum-based chemotherapy on subsequent testicular function and fertility in boys with cancer
- To share or not to share data: how valid are trials evaluating first-line ovulation induction for polycystic ovary syndrome?
- DNA methylation in human sperm: a systematic review
- The effect of paternal exposure to immunosuppressive drugs on sexual function, reproductive hormones, fertility, pregnancy and offspring outcomes: a systematic review
- New era of trophoblast research: integrating morphological and molecular approaches
- Modelling human embryogenesis: embryo-like structures spark ethical and policy debate
- Access to and sustainability of abortion services: a systematic review and meta-analysis for the National Institute of Health and Care Excellence—new clinical guidelines for England
- Reply: Possible treatment associated cancer in endometriosis
- Possible treatment-associated cancer in endometriosis
- Does an association exist between menstrual cycle length within the normal range and ovarian reserve biomarkers during the reproductive years? A systematic review and meta-analysis
- Perfluoroalkyl and polyfluoroalkyl substances (PFAS) and their effects on the ovary
- C-reactive protein and ART outcomes: a systematic review
- Studying human reproductive biology through single-cell analysis and in vitro differentiation of stem cells into germ cell-like cells
- Risk of gestational diabetes mellitus in women achieving singleton pregnancy spontaneously or after ART: a systematic review and meta-analysis
- Investigation of human trophoblast invasion in vitro
- Reply: Sperm retrieval rates by micro-TESE versus conventional TESE in men with non-obstructive azoospermia—the assumption of independence in effects sizes might lead to misleading conclusions
- Sperm retrieval rates by micro-TESE versus conventional TESE in men with non-obstructive azoospermia—the assumption of independence in effect sizes might lead to misleading conclusions
- Progesterone receptor ligands for the treatment of endometriosis: the mechanisms behind therapeutic success and failure
- The functions of CAP superfamily proteins in mammalian fertility and disease
- Brain-derived neurotrophic factor (BDNF) expression and function in the mammalian reproductive Tract
- Advanced paternal age is associated with an increased risk of spontaneous miscarriage: a systematic review and meta-analysis
- The fundamental role of the endocannabinoid system in endometrium and placenta: implications in pathophysiological aspects of uterine and pregnancy disorders
- Haem oxygenases play a pivotal role in placental physiology and pathology
- Haploid male germ cells—the Grand Central Station of protein transport
- Review of injection techniques for spermatogonial stem cell transplantation
- Cancer-associated mutations in endometriosis: shedding light on the pathogenesis and pathophysiology
- Early life factors for endometriosis: a systematic review
- Chromosomal mosaicism in human blastocysts: the ultimate diagnostic dilemma
- Hypothetical roadmap towards endometriosis: prenatal endocrine-disrupting chemical pollutant exposure, anogenital distance, gut-genital microbiota and subclinical infections
- Recurrent pregnancy loss: diagnostic workup after two or three pregnancy losses? A systematic review of the literature and meta-analysis
Human Reproduction Update: current issue
- New era of trophoblast research: integrating morphological and molecular approaches
- Possible treatment-associated cancer in endometriosis
- Reply: Possible treatment associated cancer in endometriosis
- C-reactive protein and ART outcomes: a systematic review
- Perfluoroalkyl and polyfluoroalkyl substances (PFAS) and their effects on the ovary
- Studying human reproductive biology through single-cell analysis and in vitro differentiation of stem cells into germ cell-like cells
- The dawn of the future: 30 years from the first biopsy of a human embryo. The detailed history of an ongoing revolution
- Investigation of human trophoblast invasion in vitro
- Risk of gestational diabetes mellitus in women achieving singleton pregnancy spontaneously or after ART: a systematic review and meta-analysis
- Sperm retrieval rates by micro-TESE versus conventional TESE in men with non-obstructive azoospermia—the assumption of independence in effect sizes might lead to misleading conclusions
- Reply: Sperm retrieval rates by micro-TESE versus conventional TESE in men with non-obstructive azoospermia—the assumption of independence in effects sizes might lead to misleading conclusions
- Progesterone receptor ligands for the treatment of endometriosis: the mechanisms behind therapeutic success and failure
- Brain-derived neurotrophic factor (BDNF) expression and function in the mammalian reproductive Tract
- The functions of CAP superfamily proteins in mammalian fertility and disease
- Advanced paternal age is associated with an increased risk of spontaneous miscarriage: a systematic review and meta-analysis
- The fundamental role of the endocannabinoid system in endometrium and placenta: implications in pathophysiological aspects of uterine and pregnancy disorders
- Haem oxygenases play a pivotal role in placental physiology and pathology
- Haploid male germ cells—the Grand Central Station of protein transport
- Erratum. Chromosomal mosaicism in human blastocysts: the ultimate diagnostic dilemma
- Review of injection techniques for spermatogonial stem cell transplantation
- Cancer-associated mutations in endometriosis: shedding light on the pathogenesis and pathophysiology
- Early life factors for endometriosis: a systematic review
- Chromosomal mosaicism in human blastocysts: the ultimate diagnostic dilemma
- Hypothetical roadmap towards endometriosis: prenatal endocrine-disrupting chemical pollutant exposure, anogenital distance, gut-genital microbiota and subclinical infections
- Recurrent pregnancy loss: diagnostic workup after two or three pregnancy losses? A systematic review of the literature and meta-analysis
- Diagnosing adenomyosis: an integrated clinical and imaging approach
- Long-acting reversible contraception immediately after medical abortion: systematic review with meta-analyses
- Identifying biomarkers for predicting successful embryo implantation: applying single to multi-OMICs to improve reproductive outcomes
- Interest in expanded carrier screening among individuals and couples in the general population: systematic review of the literature
- The role of microRNAs in ovarian function and the transition toward novel therapeutic strategies in fertility preservation: from bench to future clinical application
Human Reproduction Update: open access
- Impacts of platinum-based chemotherapy on subsequent testicular function and fertility in boys with cancer
- The effect of paternal exposure to immunosuppressive drugs on sexual function, reproductive hormones, fertility, pregnancy and offspring outcomes: a systematic review
- Perfluoroalkyl and polyfluoroalkyl substances (PFAS) and their effects on the ovary
- Risk of gestational diabetes mellitus in women achieving singleton pregnancy spontaneously or after ART: a systematic review and meta-analysis
- Progesterone receptor ligands for the treatment of endometriosis: the mechanisms behind therapeutic success and failure
- Advanced paternal age is associated with an increased risk of spontaneous miscarriage: a systematic review and meta-analysis
- The fundamental role of the endocannabinoid system in endometrium and placenta: implications in pathophysiological aspects of uterine and pregnancy disorders
- Recurrent pregnancy loss: diagnostic workup after two or three pregnancy losses? A systematic review of the literature and meta-analysis
- Cardiometabolic health in offspring of women with PCOS compared to healthy controls: a systematic review and individual participant data meta-analysis
- Human sperm ion channel (dys)function: implications for fertilization
- Ovarian damage from chemotherapy and current approaches to its protection
- Role of angiogenesis in adenomyosis-associated abnormal uterine bleeding and subfertility: a systematic review
- Adherence to review protocol and rigorous methodology are the pre-requisites of a well-conducted systematic review
- The association between endometriosis and autoimmune diseases: a systematic review and meta-analysis
- Effect of environmental and pharmaceutical exposures on fetal testis development and function: a systematic review of human experimental data
- Potential roles for the kisspeptin/kisspeptin receptor system in implantation and placentation
- Neurotrophins and glial cell line-derived neurotrophic factor in the ovary: physiological and pathophysiological implications
- How can we improve oncofertility care for patients? A systematic scoping review of current international practice and models of care
- Epigenetic regulation in development: is the mouse a good model for the human?
- The risk of TESE-induced hypogonadism: a systematic review and meta-analysis
- Trophoblast retrieval and isolation from the cervix: origins of cervical trophoblasts and their potential value for risk assessment of ongoing pregnancies
- Testicular organoids: a new model to study the testicular microenvironment in vitro?
- The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance—challenges and future research opportunities
- The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance—challenges and future research opportunities
- The management of menopause in women with a history of endometriosis: a systematic review
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