Human Reproduction Update (2019 IF: 12.684) is the leading journal in its field, ranked first in the category of Obstetrics & Gynecology. The journal publishes comprehensive and systematic review articles in human reproductive physiology and medicine.
Basic, transitional and clinical topics related to reproduction are of primary interest. This includes all the relevant areas of andrology, embryology, infertility, gynaecology, pregnancy, reproductive endocrinology, reproductive epidemiology, reproductive genetics, reproductive immunology, and reproductive oncology.
Human Reproduction Update is published on behalf of the European Society of Human Reproduction and Embryology (ESHRE). The highest scientific and editorial standards are maintained.
Human Reproduction Update: advance access
- FoxO1 is a cell-specific core transcription factor for endometrial remodeling and homeostasis during menstrual cycle and early pregnancy
- Embryo implantation in the laboratory: an update on current techniques
- Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction
- Maternal and neonatal outcome and children’s development after medically assisted reproduction with in-vitro matured oocytes—a systematic review and meta-analysis
- Risk of foetal harm with letrozole use in fertility treatment: a systematic review and meta-analysis
- Reply: Will Single-Cell RNAseq decipher stem cells biology in normal and cancerous tissues?
- Will Single-Cell RNAseq decipher stem cells biology in normal and cancerous tissues?
- Is there an association between paternal age and aneuploidy? Evidence from young donor oocyte-derived embryos: a systematic review and individual patient data meta-analysis
- Fertility preservation for prepubertal boys: lessons learned from the past and update on remaining challenges towards clinical translation
- Endometrial function in women with polycystic ovary syndrome: a comprehensive review
- Nanoparticles in pregnancy: the next frontier in reproductive therapeutics
- Neurophysiology of cognitive behavioural therapy, deep breathing and progressive muscle relaxation used in conjunction with ART treatments: a narrative review
- IVF and other ART in low- and middle-income countries: a systematic landscape analysis
- The other face of advanced paternal age: a scoping review of its terminological, social, public health, psychological, ethical and regulatory aspects
- Endometriosis and cancer: a systematic review and meta-analysis
- Preconception genome medicine: current state and future perspectives to improve infertility diagnosis and reproductive and health outcomes based on individual genomic data
- Mild versus conventional ovarian stimulation for IVF in poor, normal and hyper-responders: a systematic review and meta-analysis
- Persistent organic pollutants and couple fecundability: a systematic review
- Plants as source of new therapies for endometriosis: a review of preclinical and clinical studies
- Over-the-counter analgesics during pregnancy: a comprehensive review of global prevalence and offspring safety
- Molecular genetics of infertility: loss-of-function mutations in humans and corresponding knockout/mutated mice
- Immunological changes associated with adenomyosis: a systematic review
- Recovery of menses after functional hypothalamic amenorrhoea: if, when and why
- Outcomes of pregnancies using donor sperm compared with those using partner sperm: systematic review and meta-analysis
- Endometriosis recurrence following post-operative hormonal suppression: a systematic review and meta-analysis
- The development of the human uterus: morphogenesis to menarche
- Metabolic co-dependence of the oocyte and cumulus cells: essential role in determining oocyte developmental competence
- Progestins for pituitary suppression during ovarian stimulation for ART: a comprehensive and systematic review including meta-analyses
- Long-term cardiometabolic disease risk in women with PCOS: a systematic review and meta-analysis
- Impacts of platinum-based chemotherapy on subsequent testicular function and fertility in boys with cancer
Human Reproduction Update: current issue
- Over-the-counter analgesics during pregnancy: a comprehensive review of global prevalence and offspring safety
- Molecular genetics of infertility: loss-of-function mutations in humans and corresponding knockout/mutated mice
- Immunological changes associated with adenomyosis: a systematic review
- Recovery of menses after functional hypothalamic amenorrhoea: if, when and why
- Outcomes of pregnancies using donor sperm compared with those using partner sperm: systematic review and meta-analysis
- Current approaches and developments in transcript profiling of the human placenta
- Endometriosis recurrence following post-operative hormonal suppression: a systematic review and meta-analysis
- The development of the human uterus: morphogenesis to menarche
- Metabolic co-dependence of the oocyte and cumulus cells: essential role in determining oocyte developmental competence
- Progestins for pituitary suppression during ovarian stimulation for ART: a comprehensive and systematic review including meta-analyses
- Long-term cardiometabolic disease risk in women with PCOS: a systematic review and meta-analysis
- To share or not to share data: how valid are trials evaluating first-line ovulation induction for polycystic ovary syndrome?
- Impacts of platinum-based chemotherapy on subsequent testicular function and fertility in boys with cancer
- DNA methylation in human sperm: a systematic review
- The effect of paternal exposure to immunosuppressive drugs on sexual function, reproductive hormones, fertility, pregnancy and offspring outcomes: a systematic review
- New era of trophoblast research: integrating morphological and molecular approaches
- Modelling human embryogenesis: embryo-like structures spark ethical and policy debate
- Access to and sustainability of abortion services: a systematic review and meta-analysis for the National Institute of Health and Care Excellence—new clinical guidelines for England
- Possible treatment-associated cancer in endometriosis
- Reply: Possible treatment associated cancer in endometriosis
- Does an association exist between menstrual cycle length within the normal range and ovarian reserve biomarkers during the reproductive years? A systematic review and meta-analysis
- Perfluoroalkyl and polyfluoroalkyl substances (PFAS) and their effects on the ovary
- C-reactive protein and ART outcomes: a systematic review
- Studying human reproductive biology through single-cell analysis and in vitro differentiation of stem cells into germ cell-like cells
- The dawn of the future: 30 years from the first biopsy of a human embryo. The detailed history of an ongoing revolution
- Investigation of human trophoblast invasion in vitro
- Risk of gestational diabetes mellitus in women achieving singleton pregnancy spontaneously or after ART: a systematic review and meta-analysis
- Reply: Sperm retrieval rates by micro-TESE versus conventional TESE in men with non-obstructive azoospermia—the assumption of independence in effects sizes might lead to misleading conclusions
- Sperm retrieval rates by micro-TESE versus conventional TESE in men with non-obstructive azoospermia—the assumption of independence in effect sizes might lead to misleading conclusions
- Progesterone receptor ligands for the treatment of endometriosis: the mechanisms behind therapeutic success and failure
Human Reproduction Update: open access
- IVF and other ART in low- and middle-income countries: a systematic landscape analysis
- Mild versus conventional ovarian stimulation for IVF in poor, normal and hyper-responders: a systematic review and meta-analysis
- Current approaches and developments in transcript profiling of the human placenta
- Endometriosis recurrence following post-operative hormonal suppression: a systematic review and meta-analysis
- Long-term cardiometabolic disease risk in women with PCOS: a systematic review and meta-analysis
- Impacts of platinum-based chemotherapy on subsequent testicular function and fertility in boys with cancer
- The effect of paternal exposure to immunosuppressive drugs on sexual function, reproductive hormones, fertility, pregnancy and offspring outcomes: a systematic review
- Perfluoroalkyl and polyfluoroalkyl substances (PFAS) and their effects on the ovary
- Risk of gestational diabetes mellitus in women achieving singleton pregnancy spontaneously or after ART: a systematic review and meta-analysis
- Progesterone receptor ligands for the treatment of endometriosis: the mechanisms behind therapeutic success and failure
- Advanced paternal age is associated with an increased risk of spontaneous miscarriage: a systematic review and meta-analysis
- The fundamental role of the endocannabinoid system in endometrium and placenta: implications in pathophysiological aspects of uterine and pregnancy disorders
- Recurrent pregnancy loss: diagnostic workup after two or three pregnancy losses? A systematic review of the literature and meta-analysis
- Cardiometabolic health in offspring of women with PCOS compared to healthy controls: a systematic review and individual participant data meta-analysis
- Human sperm ion channel (dys)function: implications for fertilization
- Ovarian damage from chemotherapy and current approaches to its protection
- Role of angiogenesis in adenomyosis-associated abnormal uterine bleeding and subfertility: a systematic review
- Adherence to review protocol and rigorous methodology are the pre-requisites of a well-conducted systematic review
- The association between endometriosis and autoimmune diseases: a systematic review and meta-analysis
- Effect of environmental and pharmaceutical exposures on fetal testis development and function: a systematic review of human experimental data
- Potential roles for the kisspeptin/kisspeptin receptor system in implantation and placentation
- Neurotrophins and glial cell line-derived neurotrophic factor in the ovary: physiological and pathophysiological implications
- How can we improve oncofertility care for patients? A systematic scoping review of current international practice and models of care
- Epigenetic regulation in development: is the mouse a good model for the human?
- The risk of TESE-induced hypogonadism: a systematic review and meta-analysis
- Trophoblast retrieval and isolation from the cervix: origins of cervical trophoblasts and their potential value for risk assessment of ongoing pregnancies
- Testicular organoids: a new model to study the testicular microenvironment in vitro?
- The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance—challenges and future research opportunities
- The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance—challenges and future research opportunities
- The management of menopause in women with a history of endometriosis: a systematic review
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