Molecular Human Reproduction (2019 IF: 3.636) publishes articles on the basic science of human reproductive physiology and pathology, endocrinology, andrology, gonadal function, gametogenesis, fertilization, embryo development, implantation, pregnancy and contraception. Reproductive genetics is also an important part of Molecular Human Reproduction.
Studies on animal models are welcome as long as a clear relevance to human reproduction can be shown. Mechanistic studies and those exploring reproductive diversity/uniformity between species are encouraged. Published papers include peer-reviewed original research reports and short ‘New Research Horizon’ review articles.
Molecular Human Reproduction: advance access
- Hypoxia-inducible factor-1β is essential for upregulation of the hypoxia‐induced FLT1 gene in placental trophoblasts
- G-CSF and IL-6 may be involved in formation of endometriosis lesions by increasing the expression of angiogenic factors in neutrophils
- HENMT1 is involved in the maintenance of normal female fertility in the mouse
- The human sperm basal body is a complex centrosome important for embryo pre-implantation development
- Transcriptional regulation of LGALS9 by HAND2 and FOXO1 in human endometrial stromal cells in women with regular cycles
- The proteomes of endometrial stromal cell-derived extracellular vesicles following a decidualising stimulus define the cells’ potential for decidualisation success
- Uterine kisspeptin receptor critically regulates epithelial estrogen receptor Α transcriptional activity at the time of embryo implantation in a mouse model
- NLRP3 Promotes Endometrial Receptivity by Inducing Epithelial-Mesenchymal Transition of the Endometrial Epithelium
- A mouse testis serine protease, TESP1, as the potential SPINK3 receptor protein on mouse sperm acrosome
- A pathogenic DMC1 frameshift mutation causes non-obstructive azoospermia but not primary ovarian insufficiency in humans
- Immune cells and Notch1 signaling appear to drive the epithelial to mesenchymal transition in the development of adenomyosis in mice
- Intentional endometrial injury enhances angiogenesis through increased production and activation of MMP-9 by TNF-α and MMP-3 in a mouse model
- Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization
- Differential expression of microRNAs in human endometrium after implantation of an intrauterine contraceptive device containing copper
- Leukemia inhibitory factor modulates the differentiation of granulosa cells during sheep in vitro preantral to antral follicle development and improves oocyte meiotic competence
- Integrated stress response control of granulosa cell translation and proliferation during normal ovarian follicle development
- MicroRNA-125a-5p modulates the proliferation and apoptosis of TM4 Sertoli cells by targeting RAB3D and regulating the PI3K/AKT signaling pathway
- LncRNA LINC01088 inhibits the function of trophoblast cells, activates the MAPK signaling pathway and associates with recurrent pregnancy loss
- The COP9 signalosome subunit 3 is necessary for early embryo survival by way of a stable protein deposit in mouse oocytes
- Acetylcholine ameliorated hypoxia-induced oxidative stress and apoptosis in trophoblast cells via p38 MAPK/NF-κB pathway
- Increased miR-6875-5p inhibits plasmacytoid dendritic cell differentiation via the STAT3/E2-2 pathway in recurrent spontaneous abortion
- The subcortical maternal complex: emerging roles and novel perspectives
- The paternal toolbox for embryo development and health
- Reverse transcription priming methods affect normalisation choices for gene expression levels in oocytes and early embryos
- Cortisol induces follicle regression, while FSH prevents cortisol-induced follicle regression in pigs
- miRNA-149 targets PARP-2 in endometrial epithelial and stromal cells to regulate the trophoblast attachment process
- Testicular adenosine acts as a pro-inflammatory molecule: role of testicular peritubular cells
- Endometrial epithelial-mesenchymal transition (EMT) by menstruation-related inflammatory factors during hypoxia
- Two alternative methods for the retrieval of somatic cell populations from the mouse ovary
- The RNA content of human sperm reflects prior events in spermatogenesis and potential post-fertilization effects
Molecular Human Reproduction: current issue
- HENMT1 is involved in the maintenance of normal female fertility in the mouse
- The human sperm basal body is a complex centrosome important for embryo preimplantation development
- Uterine kisspeptin receptor critically regulates epithelial estrogen receptor α transcriptional activity at the time of embryo implantation in a mouse model
- NLRP3 promotes endometrial receptivity by inducing epithelial–mesenchymal transition of the endometrial epithelium
- A pathogenic DMC1 frameshift mutation causes nonobstructive azoospermia but not primary ovarian insufficiency in humans
- Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization
- Differential expression of microRNAs in human endometrium after implantation of an intrauterine contraceptive device containing copper
- Leukaemia inhibitory factor modulates the differentiation of granulosa cells during sheep in vitro preantral to antral follicle development and improves oocyte meiotic competence
- Call for papers: epigenetic regulation of reproduction in human and in animal models
- Epigenetic regulation of reproduction in human and in animal models
- MicroRNA-125a-5p modulates the proliferation and apoptosis of TM4 Sertoli cells by targeting RAB3D and regulating the PI3K/AKT signaling pathway
- The paternal toolbox for embryo development and health
- The subcortical maternal complex: emerging roles and novel perspectives
- Reverse transcription priming methods affect normalisation choices for gene expression levels in oocytes and early embryos
- Cortisol induces follicle regression, while FSH prevents cortisol-induced follicle regression in pigs
- miRNA-149 targets PARP-2 in endometrial epithelial and stromal cells to regulate the trophoblast attachment process
- Testicular adenosine acts as a pro-inflammatory molecule: role of testicular peritubular cells
- Endometrial epithelial–mesenchymal transition (EMT) by menstruation-related inflammatory factors during hypoxia
- Two alternative methods for the retrieval of somatic cell populations from the mouse ovary
- The RNA content of human sperm reflects prior events in spermatogenesis and potential post-fertilization effects
- Deciphering balanced translocations in infertile males by next-generation sequencing to identify candidate genes for spermatogenesis disorders
- Lysophosphatidic acid improves oocyte quality during IVM by activating the ERK1/2 pathway in cumulus cells and oocytes
- Oocyte-secreted factors strongly stimulate sFRP4 expression in human cumulus cells
- Thank you to our reviewers – 2020
- Excess fibronectin 1 participates in pathogenesis of pre-eclampsia by promoting apoptosis and autophagy in vascular endothelial cells
- Limited proteolysis by acrosin affects sperm-binding and mechanical resilience of the mouse zona pellucida
- An agenda for the year 2021 and onwards
- RNA N6-methyladenosine modification, spermatogenesis, and human male infertility
- Tofacitinib alters STAT3 signaling and leads to endometriosis lesion regression
- Genetic and epigenetic changes in the eutopic endometrium of women with endometriosis: association with decreased endometrial αvβ3 integrin expression
Molecular Human Reproduction: open access
- Hypoxia-inducible factor-1β is essential for upregulation of the hypoxia‐induced FLT1 gene in placental trophoblasts
- The human sperm basal body is a complex centrosome important for embryo pre-implantation development
- Increased miR-6875-5p inhibits plasmacytoid dendritic cell differentiation via the STAT3/E2-2 pathway in recurrent spontaneous abortion
- Reverse transcription priming methods affect normalisation choices for gene expression levels in oocytes and early embryos
- Two alternative methods for the retrieval of somatic cell populations from the mouse ovary
- Thank you to our reviewers – 2020
- Histone demethylase KDM4A overexpression improved the efficiency of corrected human tripronuclear zygote development
- Guidelines for biomarker discovery in endometrium: Correcting for menstrual cycle bias reveals new genes associated with uterine disorders
- Motility of efferent duct cilia aids passage of sperm cells through the male reproductive system
- Use of selective PGE2 receptor antagonists on human endometriotic stromal cells and peritoneal macrophages
- The role of ATP in the differential ability of Sr2+ to trigger Ca2+ oscillations in mouse and human eggs
- HMGA2-induced epithelial–mesenchymal transition is reversed by let-7d in intrauterine adhesions
- Embryonic fatty acid metabolism in diabetic pregnancy: the difference between embryoblasts and trophoblasts
- A tale of two cell-fates: role of the Hippo signaling pathway and transcription factors in early lineage formation in mouse preimplantation embryos
- The molecular mechanisms that underlie fragile X-associated premature ovarian insufficiency: is it RNA or protein based?
- A tale of two cell-fates: Role of the Hippo signaling pathway and transcription factors in early lineage formation in mouse preimplantation embryos
- Abnormal Cullin1 neddylation-mediated p21 accumulation participates in the pathogenesis of recurrent spontaneous abortion by regulating trophoblast cell proliferation and differentiation
- Concordance of various chromosomal errors among different parts of the embryo and the value of re-biopsy in embryos with segmental aneuploidies
- Differential tissue-specific damage caused by bacterial epididymo-orchitis in the mouse
- Towards uterus tissue engineering: a comparative study of sheep uterus decellularisation
- Comparative gonadotoxicity of the chemotherapy drugs cisplatin and carboplatin on prepubertal mouse gonads
- The spatio-temporal dynamics of mitochondrial membrane potential during oocyte maturation
- Differences in blastomere totipotency in 2-cell mouse embryos are a maternal trait mediated by asymmetric mRNA distribution
- Prolactin decreases LPS-induced inflammatory cytokines by inhibiting TLR-4/NFκB signaling in the human placenta
- Human blastocyst outgrowths recapitulate primordial germ cell specification events
- Continuous behavioural ‘switching’ in human spermatozoa and its regulation by Ca2+-mobilising stimuli
- Emerging concepts of shear stress in placental development and function
- Emerging concepts of shear stress in placental development and function
- Probing human sperm metabolism using 13C-magnetic resonance spectroscopy
- Concordance between different trophectoderm biopsy sites and the inner cell mass of chromosomal composition measured with a next-generation sequencing platform
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