Molecular Human Reproduction (2019 IF: 3.636) publishes articles on the basic science of human reproductive physiology and pathology, endocrinology, andrology, gonadal function, gametogenesis, fertilization, embryo development, implantation, pregnancy and contraception. Reproductive genetics is also an important part of Molecular Human Reproduction.
Studies on animal models are welcome as long as a clear relevance to human reproduction can be shown. Mechanistic studies and those exploring reproductive diversity/uniformity between species are encouraged. Published papers include peer-reviewed original research reports and short ‘New Research Horizon’ review articles.
Molecular Human Reproduction: advance access
- Profiling (placental) DNA methylation in cell-free DNA across gestation: the Rotterdam Periconception Cohort
- Single-cell metabolomics reveals that bisphosphoglycerate mutase influences oocyte maturation through glucose metabolism
- Cellular Prion: A novel regulator of decidual cell function at the maternal fetal interface
- Roles of chromosomal and gonadal sex in the fetal and placental responses to maternal food restriction in mice
- OTUD1 inhibits endometriosis fibrosis by deubiquitinating MADH7
- Effects of chronic particulate matter exposure on endometriosis-associated signaling pathways and disease progression
- Exploring and validating the marmoset as a primate model for chromosomal instability in early development
- Protein-targeting reverse genetic approaches: the future of oocyte and preimplantation embryo research
- Human platelet-rich plasma promotes primordial follicle activation via the PI3K/akt signaling pathway
- A comprehensive study of the sperm head defects in MMAF condition and their impact on embryo development in mice
- Bioenergetics of human spermatozoa in patients with testicular germ cell tumours
- MCP-1 promotes ILK phosphorylation at Ser246 during endometriosis development and affects the pregnancy outcome
- An aberrant protamine ratio is associated with decreased H4ac levels in murine and human sperm
- Mouse modeling of familial human SYCE1 c.197-2A>G splice site mutation leads to meiotic recombination failure and non-obstructive azoospermia
- Pro-cumulin addition in a biphasic in vitro oocyte maturation system modulates human oocyte and cumulus cell transcriptomes
- Animal and vegetal materials of mouse oocytes segregate at first zygotic cleavage: a simple mechanism that makes the 2-cell blastomeres differ reciprocally from the start
- Endometrial stromal cell signaling and microRNA exosome content in women with adenomyosis
- Gene expression analysis of ovarian follicles and stromal cells in girls with Turner syndrome
- mTOR inhibitors as potential therapeutics for endometriosis: A narrative review
- Hypoxia-inducible factor-1β is essential for upregulation of the hypoxia‐induced FLT1 gene in placental trophoblasts
- G-CSF and IL-6 may be involved in formation of endometriosis lesions by increasing the expression of angiogenic factors in neutrophils
- HENMT1 is involved in the maintenance of normal female fertility in the mouse
- The human sperm basal body is a complex centrosome important for embryo pre-implantation development
- Transcriptional regulation of LGALS9 by HAND2 and FOXO1 in human endometrial stromal cells in women with regular cycles
- The proteomes of endometrial stromal cell-derived extracellular vesicles following a decidualising stimulus define the cells’ potential for decidualisation success
- Uterine kisspeptin receptor critically regulates epithelial estrogen receptor Α transcriptional activity at the time of embryo implantation in a mouse model
- NLRP3 Promotes Endometrial Receptivity by Inducing Epithelial-Mesenchymal Transition of the Endometrial Epithelium
- A mouse testis serine protease, TESP1, as the potential SPINK3 receptor protein on mouse sperm acrosome
- A pathogenic DMC1 frameshift mutation causes non-obstructive azoospermia but not primary ovarian insufficiency in humans
- Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization
Molecular Human Reproduction: current issue
- Profiling (placental) DNA methylation in cell-free DNA across gestation: the Rotterdam Periconception Cohort
- Single-cell metabolomics reveals that bisphosphoglycerate mutase influences oocyte maturation through glucose metabolism
- Effects of chronic particulate matter exposure on endometriosis-associated signaling pathways and disease progression
- Correction to: Understanding the heterogeneity of natural killer cells at the maternal–fetal interface: implications for pregnancy health and disease
- Exploring and validating the marmoset as a primate model for chromosomal instability in early development
- Protein-targeting reverse genetic approaches: the future of oocyte and preimplantation embryo research
- Human platelet-rich plasma promotes primordial follicle activation via the PI3K/Akt signaling pathway
- A comprehensive study of the sperm head defects in MMAF condition and their impact on embryo development in mice
- Bioenergetics of human spermatozoa in patients with testicular germ cell tumours
- MCP-1 promotes ILK phosphorylation at Ser246 during endometriosis development and affects the pregnancy outcome
- An aberrant protamine ratio is associated with decreased H4ac levels in murine and human sperm
- Mouse modeling of familial human SYCE1 c.197-2A>G splice site mutation leads to meiotic recombination failure and non-obstructive azoospermia
- Pro-cumulin addition in a biphasic in vitro oocyte maturation system modulates human oocyte and cumulus cell transcriptomes
- Animal and vegetal materials of mouse oocytes segregate at first zygotic cleavage: a simple mechanism that makes the two-cell blastomeres differ reciprocally from the start
- Ectopic endometrial stromal cell-derived extracellular vesicles encapsulating microRNA-25-3p induce endometrial collagen I deposition impairing decidualization in endometriosis
- Endometrial stromal cell signaling and microRNA exosome content in women with adenomyosis
- Gene expression analysis of ovarian follicles and stromal cells in girls with Turner syndrome
- mTOR inhibitors as potential therapeutics for endometriosis: a narrative review
- Understanding the heterogeneity of natural killer cells at the maternal–fetal interface: implications for pregnancy health and disease
- WD-repeat containing protein-61 regulates endometrial epithelial cell adhesion indicating an important role in receptivity
- Placental gene therapy in nonhuman primates: a pilot study of maternal, placental, and fetal response to non-viral, polymeric nanoparticle delivery of IGF1
- HENMT1 is involved in the maintenance of normal female fertility in the mouse
- The human sperm basal body is a complex centrosome important for embryo preimplantation development
- Uterine kisspeptin receptor critically regulates epithelial estrogen receptor α transcriptional activity at the time of embryo implantation in a mouse model
- NLRP3 promotes endometrial receptivity by inducing epithelial–mesenchymal transition of the endometrial epithelium
- A pathogenic DMC1 frameshift mutation causes nonobstructive azoospermia but not primary ovarian insufficiency in humans
- Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization
- Differential expression of microRNAs in human endometrium after implantation of an intrauterine contraceptive device containing copper
- Leukaemia inhibitory factor modulates the differentiation of granulosa cells during sheep in vitro preantral to antral follicle development and improves oocyte meiotic competence
- Call for papers: epigenetic regulation of reproduction in human and in animal models
Molecular Human Reproduction: open access
- Hypoxia-inducible factor-1β is essential for upregulation of the hypoxia‐induced FLT1 gene in placental trophoblasts
- The human sperm basal body is a complex centrosome important for embryo pre-implantation development
- Increased miR-6875-5p inhibits plasmacytoid dendritic cell differentiation via the STAT3/E2-2 pathway in recurrent spontaneous abortion
- Reverse transcription priming methods affect normalisation choices for gene expression levels in oocytes and early embryos
- Two alternative methods for the retrieval of somatic cell populations from the mouse ovary
- Thank you to our reviewers – 2020
- Histone demethylase KDM4A overexpression improved the efficiency of corrected human tripronuclear zygote development
- Guidelines for biomarker discovery in endometrium: Correcting for menstrual cycle bias reveals new genes associated with uterine disorders
- Motility of efferent duct cilia aids passage of sperm cells through the male reproductive system
- Use of selective PGE2 receptor antagonists on human endometriotic stromal cells and peritoneal macrophages
- The role of ATP in the differential ability of Sr2+ to trigger Ca2+ oscillations in mouse and human eggs
- HMGA2-induced epithelial–mesenchymal transition is reversed by let-7d in intrauterine adhesions
- Embryonic fatty acid metabolism in diabetic pregnancy: the difference between embryoblasts and trophoblasts
- A tale of two cell-fates: role of the Hippo signaling pathway and transcription factors in early lineage formation in mouse preimplantation embryos
- The molecular mechanisms that underlie fragile X-associated premature ovarian insufficiency: is it RNA or protein based?
- A tale of two cell-fates: Role of the Hippo signaling pathway and transcription factors in early lineage formation in mouse preimplantation embryos
- Abnormal Cullin1 neddylation-mediated p21 accumulation participates in the pathogenesis of recurrent spontaneous abortion by regulating trophoblast cell proliferation and differentiation
- Concordance of various chromosomal errors among different parts of the embryo and the value of re-biopsy in embryos with segmental aneuploidies
- Differential tissue-specific damage caused by bacterial epididymo-orchitis in the mouse
- Towards uterus tissue engineering: a comparative study of sheep uterus decellularisation
- Comparative gonadotoxicity of the chemotherapy drugs cisplatin and carboplatin on prepubertal mouse gonads
- The spatio-temporal dynamics of mitochondrial membrane potential during oocyte maturation
- Differences in blastomere totipotency in 2-cell mouse embryos are a maternal trait mediated by asymmetric mRNA distribution
- Prolactin decreases LPS-induced inflammatory cytokines by inhibiting TLR-4/NFκB signaling in the human placenta
- Human blastocyst outgrowths recapitulate primordial germ cell specification events
- Continuous behavioural ‘switching’ in human spermatozoa and its regulation by Ca2+-mobilising stimuli
- Emerging concepts of shear stress in placental development and function
- Emerging concepts of shear stress in placental development and function
- Probing human sperm metabolism using 13C-magnetic resonance spectroscopy
- Concordance between different trophectoderm biopsy sites and the inner cell mass of chromosomal composition measured with a next-generation sequencing platform