Molecular Human Reproduction (2019 IF: 3.636) publishes articles on the basic science of human reproductive physiology and pathology, endocrinology, andrology, gonadal function, gametogenesis, fertilization, embryo development, implantation, pregnancy and contraception. Reproductive genetics is also an important part of Molecular Human Reproduction.
Studies on animal models are welcome as long as a clear relevance to human reproduction can be shown. Mechanistic studies and those exploring reproductive diversity/uniformity between species are encouraged. Published papers include peer-reviewed original research reports and short ‘New Research Horizon’ review articles.
Molecular Human Reproduction: advance access
- Embryonic fatty acid metabolism in diabetic pregnancy: the difference between embryoblasts and trophoblasts
- Revisiting the action of steroids and triterpenoids on the human sperm Ca2+ channel CatSper
- Comparative study of pre-implantation development following distinct assisted oocyte activation protocols in a PLC-Zeta knockout mouse model
- Palmitic acid induces inflammation in placental trophoblasts and impairs their migration toward smooth muscle cells through plasminogen activator inhibitor-1
- High throughput sequencing reveals landscapes of female germ cell development
- Decorin production by the human decidua: role in decidual cell maturation
- A tale of two cell-fates: role of the Hippo signaling pathway and transcription factors in early lineage formation in mouse preimplantation embryos
- The molecular mechanisms that underlie fragile X-associated premature ovarian insufficiency: is it RNA or protein based?
- Ionomycin induced mouse oocyte activation can disrupt preimplantation embryo development through increased reactive oxygen species reaction and DNA damage
- Pubertal down regulation of Tetraspanin 8 in testicular Sertoli cells is crucial for male fertility
- Analysis of accessible chromatin landscape in the inner cell mass and trophectoderm of human blastocysts
- A tale of two cell-fates: Role of the Hippo signaling pathway and transcription factors in early lineage formation in mouse preimplantation embryos
- The alarmin interleukin-1α causes preterm birth through the NLRP3 inflammasome
- Mimicking the temperature gradient between the sow’s oviduct and uterus improves in-vitro embryo culture output
- Premature ovarian insufficiency in the XO female mouse on the C57BL/6J genetic background
- Vitrification-induced activation of lysosomal cathepsin B perturbs spindle assembly checkpoint function in mouse oocytes
- STAG3 homozygous missense variant causes primary ovarian insufficiency and male non-obstructive azoospermia
- Effects of vitrification and the superovulated environment on placental function and fetal growth in an IVF mouse model
- Functional Changes in Decidual Mesenchymal Stem/Stromal Cells are Associated with Spontaneous Onset of Labour
- Perinatal Exposure to High Dietary Advanced Glycation End-Products Affects the Reproductive System in Female Offspring in Mice
- BHLHE40 plays a pathological role in pre-eclampsia through up-regulating SNX16 by transcriptional inhibition of miR-196a-5p
- miR-130b regulates gap junctional intercellular communication through connexin 43 in granulosa cells from patients with polycystic ovary syndrome
- Impact of endoplasmic reticulum stress on oocyte aging mechanisms
- Unraveling the mechanisms of chemotherapy-induced damage to human primordial follicle reserve: road to developing therapeutics for fertility preservation and reversing ovarian aging
- Letter: COVID-19 and human reproduction: hypothesis need to be investigated
- Human chorionic gonadotropin improves endometrial receptivity by increasing the expression of homeobox A10
- Reply: COVID-19 and human reproduction: hypothesis need to be investigated
- A prominent environmental endocrine disruptor, 4-nonylphenol, promotes endometriosis development via plasmacytoid dendritic cells
- Platelet-derived growth factor B restores vascular barrier integrity and diminishes permeability in ovarian hyperstimulation syndrome
- Modelling fibroid pathology: development and manipulation of a myometrial smooth muscle cell macromolecular crowding model to alter extracellular matrix deposition
Molecular Human Reproduction: current issue
- Effects of vitrification and the superovulated environment on placental function and fetal growth in an IVF mouse model
- Platelet-derived growth factor B restores vascular barrier integrity and diminishes permeability in ovarian hyperstimulation syndrome
- miR-130b regulates gap junctional intercellular communication through connexin 43 in granulosa cells from patients with polycystic ovary syndrome
- Functional changes in decidual mesenchymal stem/stromal cells are associated with spontaneous onset of labour
- Perinatal exposure to high dietary advanced glycation end products affects the reproductive system in female offspring in mice
- BHLHE40 plays a pathological role in pre-eclampsia through upregulating SNX16 by transcriptional inhibition of miR-196a-5p
- Impact of endoplasmic reticulum stress on oocyte aging mechanisms
- Unraveling the mechanisms of chemotherapy-induced damage to human primordial follicle reserve: road to developing therapeutics for fertility preservation and reversing ovarian aging
- Human chorionic gonadotropin improves endometrial receptivity by increasing the expression of homeobox A10
- Letter: COVID-19 and human reproduction: hypothesis needs to be investigated
- Reply: COVID-19 and human reproduction: hypothesis needs to be investigated
- A prominent environmental endocrine disruptor, 4-nonylphenol, promotes endometriosis development via plasmacytoid dendritic cells
- Modelling fibroid pathology: development and manipulation of a myometrial smooth muscle cell macromolecular crowding model to alter extracellular matrix deposition
- Downregulation of HDAC8 expression decreases CD163 levels and promotes the apoptosis of macrophages by activating the ERK signaling pathway in recurrent spontaneous miscarriage
- New insights into the potential mechanisms of spermatogenic failure in patients with idiopathic azoospermia
- Familial primary ovarian insufficiency associated with an SYCE1 point mutation: defective meiosis elucidated in humanized mice
- Exosomes and soluble secretome from hormone-treated endometrial epithelial cells direct embryo implantation
- The SEPT12 complex is required for the establishment of a functional sperm head–tail junction
- Potential influence of COVID-19/ACE2 on the female reproductive system
- Use of a human embryonic stem cell model to discover GABRP, WFDC2, VTCN1 and ACTC1 as markers of early first trimester human trophoblast
- Treatment with 2-methoxyestradiol increases endothelial nitric oxide synthase activity via scavenger receptor class BI in human umbilical vein endothelial cells
- Deficiency of the onco-miRNA cluster, miR-106b∼25, causes oligozoospermia and the cooperative action of miR-106b∼25 and miR-17∼92 is required to maintain male fertility
- Metabolic profile of in vitro derived human embryos is not affected by the mode of fertilization
- The initial maturation status of marmoset testicular tissues has an impact on germ cell maintenance and somatic cell response in tissue fragment culture
- The short-chain fatty acids butyrate and propionate protect against inflammation-induced activation of mediators involved in active labor: implications for preterm birth
- Zinc exocytosis is sensitive to myosin light chain kinase inhibition in mouse and human eggs
- Interleukin-37b inhibits the growth of murine endometriosis-like lesions by regulating proliferation, invasion, angiogenesis and inflammation
- Using miRNAs as diagnostic biomarkers for male infertility: opportunities and challenges
- Abnormal uterine inflammation in obstetric syndromes: molecular insights into the role of chemokine decoy receptor D6 and inflammasome NLRP3
- Follicular hormone dynamics during the midcycle surge of gonadotropins in women undergoing fertility treatment
Molecular Human Reproduction: open access
- Embryonic fatty acid metabolism in diabetic pregnancy: the difference between embryoblasts and trophoblasts
- A tale of two cell-fates: role of the Hippo signaling pathway and transcription factors in early lineage formation in mouse preimplantation embryos
- The molecular mechanisms that underlie fragile X-associated premature ovarian insufficiency: is it RNA or protein based?
- A tale of two cell-fates: Role of the Hippo signaling pathway and transcription factors in early lineage formation in mouse preimplantation embryos
- Abnormal Cullin1 neddylation-mediated p21 accumulation participates in the pathogenesis of recurrent spontaneous abortion by regulating trophoblast cell proliferation and differentiation
- Differential tissue-specific damage caused by bacterial epididymo-orchitis in the mouse
- Concordance of various chromosomal errors among different parts of the embryo and the value of re-biopsy in embryos with segmental aneuploidies
- Towards uterus tissue engineering: a comparative study of sheep uterus decellularisation
- Comparative gonadotoxicity of the chemotherapy drugs cisplatin and carboplatin on prepubertal mouse gonads
- The spatio-temporal dynamics of mitochondrial membrane potential during oocyte maturation
- Differences in blastomere totipotency in 2-cell mouse embryos are a maternal trait mediated by asymmetric mRNA distribution
- Prolactin decreases LPS-induced inflammatory cytokines by inhibiting TLR-4/NFκB signaling in the human placenta
- Human blastocyst outgrowths recapitulate primordial germ cell specification events
- Continuous behavioural ‘switching’ in human spermatozoa and its regulation by Ca2+-mobilising stimuli
- Emerging concepts of shear stress in placental development and function
- Emerging concepts of shear stress in placental development and function
- Probing human sperm metabolism using 13C-magnetic resonance spectroscopy
- Concordance between different trophectoderm biopsy sites and the inner cell mass of chromosomal composition measured with a next-generation sequencing platform
- Characterization of migratory primordial germ cells in the aorta-gonad-mesonephros of a 4.5 week-old human embryo: a toolbox to evaluate in-vitro early gametogenesis
- Metaphase II oocytes from human unilaminar follicles grown in a multi-step culture system
- Protein profile of mouse ovarian follicles grown in vitro
- Protein profile of mouse ovarian follicles grown in vitro
- Immune cell and transcriptomic analysis of the human decidua in term and preterm parturition
- 1 H Magnetic Resonance Spectroscopy of live human sperm
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